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This triggers synaptogenesis, the creation of new functional connections between neurons

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Such inflammatory changes potentially cause impaired autoregulation of blood flow (29), hypoperfusion in the brain stem (356–358), and brain tissue hypoxia (22, 23, 26, 29–101, 103, 109, 113, 127–234, 248–256, 266, 297–318, 329–359)